The Distinctive Evolution of orfX Clostridium parabotulinum Strains and Their Botulinum Neurotoxin Type A and F Gene Clusters Is Influenced by Environmental Factors and Gene Interactions via Mobile Genetic Elements
Of the seven currently known botulinum neurotoxin-producing species of Clostridium, C.parabotulinum, or C.botulinum Group I, is the species associated with the majority of human botulism cases worldwide.Phylogenetic analysis of these bacteria reveals a diverse species with multiple genomic clades.The neurotoxins they produce are also diverse, with